New Stanford-Ohio Five structural molecular biology collaboration announced for 2019

Posted on July 25, 2018

The Stanford Synchrotron Radiation Lightsource (SSRL) Structural Molecular Biology (SMB) Program at Stanford has partnered with the Five Colleges of Ohio to offer two opportunities for students and faculty to connect with the SMB program and be trained in applications of macromolecular crystallography using synchrotron radiation. The synchrotron, housed at Stanford’s SLAC National Accelerator Laboratory, offer an unparalleled resource for researchers to study our world at the atomic and molecular level using extremely bright x-rays.   The collaboration focuses on structural biology research and the applications of physical methodologies for exploring a science research questions.

SLAC Summer Undergraduate Research Opportunity in Summer 2019

The SSRL SMB program will reserve two spots for Ohio Five students to participate as interns in its 2019 summer program, matching undergraduate students from the Ohio Five who are interested in exploring structural molecular biology research with a research opportunity at SSRL in the SMB area. Over the 8-9 week internship, students will work in the laboratory conducting experiments, designing and using software, and/or measuring and analyzing data associated with research projects directed by SSRL SMB faculty and staff.  Recent student projects have included structural studies on antibiotic resistance enzyme, crystal growth, sample preparation and equipment design for structural biology research, and software/hardware developments for automated crystal screening. 

Interns will participate in lectures, professional development workshops and tours along with other interns at the SLAC facility and will conclude their work with the preparation of a 6-8-page paper and research presentation.  This internship is especially suited to Ohio Five students majoring in biology, chemistry, biochemistry, physics, computer science, engineering or mathematics.  The program will include a stipend of $500 per week for 8-9 weeks, housing, and transportation to and from Stanford. I

 Interested students should apply by January 10, 2019, using this two-step process: 1) Complete the application on the Department of Energy Science Undergraduate Laboratory (SULI) site, which will require a transcript in PDF copy and separate submission of two recommendations.  Please select SLAC National Accelerator Laboratory as the preferred laboratory and review eligibility requirements on the site.  2) Complete a notification of application in the Ohio Five online portal, including cover letter, transcript and current resume.  Decisions will be announced by March 15, 2019.

SLAC Spring 2019 Mini-Course at Ohio Five Colleges

Ohio Five science faculty are invited to participate an intensive two-day pilot short course in structural biology macromolecular crystallography led by SSLR SMB faculty, on an Ohio Five college campus in spring 2019. The course will focus on a demonstration of remote access to the SSRL macromolecular crystallography instruments on the synchrotron, offering a hands-on experience in working with crystal structure analysis and data provided by this state-of-the-art equipment.  The session include introductory overview lectures about macromolecular crystallography – how it is used, research techniques and problems it can solve -- and subsequent lectures on experimental techniques using synchrotron radiation. Using remote access to the instrumentation at SSRL, the student and faculty group will collect data on a macromolecular crystal, analyze it on the remote compute servers at SSRL, and receive results.  Future projects in faculty research or the classroom could take advantage of these capabilities, which require only a computer classroom with video screen connection and good internet service.   There would be no cost to the campuses beyond any meals or accommodations needed for Ohio Five students and faculty. Up to 10-12 students and 10-12 faculty may participate in the session, which will be scheduled at a time in spring 2019 most workable for the participants.

Ohio Five faculty members interested in participating in the short course are invited to contact Ohio Five Executive Director Sarah Stone at stones@ohio5.org or at (440) 775-5501 for more details.